Ozzy & Drix also known as The Fantastic Voyage Adventures of Osmosis Jones & Drixenol and Osmosis Jones The Animated Series is an American animated television series and a spin-off of the film Osmosis Jones and it was produced by Warner Bros. Animation. It takes place inside the body of teenager Hector Cruz (referred to by the characters as "The City of Hector"). The series premiered on September 14th, 2002 on the Kids' WB; the final episode aired July 5th, 2004.

Unlike the film it spun off from, Ozzy & Drix was entirely animated and contained no live action. It stars Phil LaMarr as the replacement for Chris Rock as Osmosis Jones, and Jeff Bennett as the replacement for David Hyde Pierce as Drix. As of July 2011, episodes of the series were still available via the Kids WB website. The show also aired on Teletoon in Canada. The show is also slightly less violent than the movie, having the characters treated like people rather than simply cells, and having none of them killed off unlike the film where Thrax managed to kill off several cells.

Summary[edit | edit source]

A year after Ozzy and Drix defeated Thrax and saved Frank from dying in Osmosis Jones, Ozzy and Drix chase a scarlet fever bacterium (possibly thanks to Frank resuming his poor eating habits) and end up getting sucked up from Frank along with the germ by a mosquito and arrive on a teenager named Hector Cruz. After some initial problems with their new home, both are installed as Private Investigators, vowing to protect the well being of Hector from any viral threat.

Trivia[edit | edit source]

  • Chris Rock and David Hyde Pierce does not reprise their roles as the titular characters

Characters[edit | edit source]

Main characters[edit | edit source]

Osmosis "Ozzy" Jones (voiced by Phil LaMarr) - An urban and funky white blood cell with little respect for authority and the main protagonist of the show. He works as a private-eye in the city of Hector. He and Drix were originally from the city of Frank, the character portrayed in the movie, although they were transferred to Hector through a mosquito while chasing a scarlet fever virus aptly named Scarlet. As most crime-fighting heroes do, Ozzy has a nearly unlimited amount of smart remarks that he uses frequently when fighting viruses, as well as sarcasm for anyone else.

Agent "Drixobenzometapetramine"/"Drix" Koldriliff (voiced by Jeff Bennett) - A straight-laced and by-the-book cold pill and Ozzy's fellow private eye and best friend, and the deuteragonist of the show. They have an office inside Hector's left retina ("prime real estate"). His right arm is a multi-launcher which launches various chemical containers stored in his torso though the most common is an ice pill which freezes villains. The right arm also contains a phone, and other gadgets including an eggbeater (apparently the only thing the arm can't do is make a decent milkshake),and a crude clamp-like claw usable as a hand. Drix's cautiousness and complete honesty (making him quite gullible), puts him at odds with the devil-may-care Ozzy. He often tries to "fit in" with the other cells in the body, usually failing to comprehend the concepts. He is fun-loving, happy go-lucky, and sometimes a comic relief and a coward instead of being tough and serious, unlike in the movie.

Hector Cruz (AKA The City of Hector) (voiced by Justin Cowden) - A Cuban-American teenager that the show revolves around. He is foolhardy, a risk taker, and somewhat ignorant, all probably to further the show's plot. He reminds Ozzy of Frank at Hector's age, reminded him that this was the age where Frank's life took a turn for the worse so decides to stay to prevent that from happening.. Hector has a dog named Uno, an older sister, and a mother and father. He is the tritagonist of the show.

City of Hector[edit | edit source]

  • Maria Amino (Tasia Valenza) - A white blood cell and a cop in the city of Hector. She speaks with a Hispanic accent. She is highly skilled at fighting and possibly the most competent cop inside of Hector except for Ozzy. She has shown to have a crush on Drix throughout the series. Her name comes from the amino acid and is also Drix's love interest.
  • Chief Gluteus (Jim Cummings) - A gruff and serious old muscle cell and the Chief of Police for the city of Hector. He often prefers to handle things himself, which usually results in disasters. His name is from Gluteus Maximus, the scientific name for the muscles in the buttock.
  • Mayor Paul Spryman (voiced by Alanna Ubach) - The teenage mayor of the city of Hector, and Ozzy's rival. Unlike Mayor Phlegmming where he is an adult and acted mature and gentlemen-like from the film, he is approximately the same age as Hector, he acts very immaturely, and often takes all the credit for the round-ups Ozzy and Drix make. His decisions often put Hector's health in extreme danger as well as sometimes being completely ridiculous, where Maria commented that he once ordered all the cells to go to the left side to see if Hector would tip over.
  • Ellen Patella (voiced by Vivica A. Fox) - An attorney-at-law who helps new cells find their place in Hector. Ozzy has a small crush on her as well, although she has no interest in him.
  • The Mole (voiced by Jeffrey Tambor) - A former secret agent, and klutz, and generally used as comic relief, he has his own adrenaline supply, and in every one of his appearances he tries to "vanish mysteriously" (failing to do so every time in comical ways). He is mostly known as very paranoid, often thinking that he is being hunted down, or people are watching him. Despite this he has a lot of contacts and apparently nothing happens in Hector that he doesn't know about, this makes him a good source of information. His role is similar to the flu shot from the movie.
  • Penicillin G (voiced by Julian Sands) - A Penicillin injected into Hector to help fight Strepfinger. He is charming, responsible, and amazingly intelligent. He currently patrols Hector's lungs. He is an obvious parody of James Bond.
  • Dander (voiced by Frank Welker) - Drix's pet dog germ that came from Hector's dog Uno, formed from the dog's saliva inside Hector's nostril. Like cells, he can shapeshift and often changes his head into Ozzy.
The Supplements
  • Vitamin A (voiced by Phil LaMarr): The leader of the Supplements who lead his team to victory by stopping the Lead-Heads who were attempting to infect Hector. Unlike Ozzy, he is very by-the-book, and has a slight resemblance to Superman.
  • Iron (voiced by Phil LaMarr): A strong, yet short tempered member of the Supplements, and the only one with no cape. Iron is a parody of the Thing> from Fantastic Four.
  • B Complex (voiced by Jim Cummings): B Complex has 3 heads and 4 legs, but only 2 arms.
  • Vitamine D (voiced by Rob Paulsen): A fast, egotistical member of the Supplements.
  • Vitamine E (voiced by Nancy Lenari): The only three-eyed female of the Supplements, who encouraged Drix to join the team.

Help from the City of Hector

  • Captain Quinine (voiced by James Belushi) A captain who lost his leg in a stomach acid accident (parodying Captain Ahab of Moby Dick).
  • The Current Dreams Studio Head (Kevin Michael Richardson): A small studio head of the subconscious network, who used a holographic head to be more powerful and scary, like the wizard in The Wizard of Oz.
  • Loretta Epstein-Barr (voiced by Kathy Najimy): The vice president of the subconscious network, who explained why the studio keeps rerunning the nightmare Hector was having.
  • Auntie Histamine (voiced by Andrea Martin): Drix's aunt who used to read lists of synthesised amino acids when Drix was young, but she accidentally became a villain when Hector abuses his nose spray when he had a cold. So when Hector uses the spray, Auntie becomes hysterical and drains all the liquids on Hector, which could have been damaging to his nose.
  • Mr. Cruz (voiced by Joe Lala): Hector's father is a helpful is very serious and strongly observant when it comes to Hector's health, attitude, and his school reports.
  • Mrs. Cruz (voiced by Alanna Ubach) Hector's mother is always looking out for Hector's health, since he is still a teenager and doesn't listen to her sometimes.
  • Hector's unnamed sister (voiced by Alanna Ubach): She is always starting an argument with Hector, because she is the older sister.
  • Christine Kolchuck (voiced by Kimberly Brooks): She is very sweet and kind, not to mention Hector's crush. Ozzy even helped save Christine from the Pneumoniac. She is also Hector's love-interest.
  • Travis Lum (voiced by Rob Paulsen): He is Hector's best friend.
  • Ricky Sales (voiced by Rob Paulsen): He is the school bully and the main antagonist of the episode Reflex.
  • Frank DeTorre: He was Ozzy and Drix's original home-body.

The City of Christine[edit | edit source]

  • Mayor Conscious Santorini (voiced by Cree Summer): She is the mayor of Christine, and she is more smart and responsible than Spryman. She even said that everyone in Christine are fans of Hector.
  • Cilia Tyson (voiced by Dawnn Lewis): Cilia is a cop in Christine who helped Ozzy stop the Pneumoniac and prove that Maximus is a traitor to the city. She was made the new police chief by the mayor. She used to dislike Ozzy.
  • 'Drixeen (voiced by Miriam Flynn): She is a dear friend to Cilia and she used to a cold pill. She looks a bit like Drix except she's green, has hair, and a right hand and left cannon, while Drix is red, has no hair, and his arm positions are the other way.

Germs and viruses[edit | edit source]

  • Ernst Strepfinger (Brad Garrett and Jim Cummings) - A powerful germ whose goal is to make Hector sick. He has a large gang of germs and viruses to do his dirty work. In "Strepfinger", Strepfinger is planning on giving Hector a nasty case of pneumonia, but in the end, he gets sucked out from his hideout in the lungs along with his pet. In "Ozzy Jr.", Strepfinger returns, but this time he has an eye patch on his right eye and his pet has an eye patch, too. He plans to infect Hector with bacteria. In "Lights Out", Ozzy and Drix use his resources to break into the Central Data Bank when everyone forgets who they are after Hector suffers a concussion. In "Tricky Ricardo", he tricks Ricardo into thinking that he's working for Strepfinger, who was planning to give Hector Cancer, but in the end, Strepfinger gets stuck on one of the cotton balls and fell down the drain of the shower. Strepfinger is a parody of the stereotypical Bond villain with a particular emphasis on Auric Goldfinger and Ernst Stavro Blofeld.
  • Mother Louse - A louse that laid its eggs on Hector's hair. It fell to its death when Drix got too close to one of Hector's hairs, but he caught Ozzy just in time and then he and Ozzy went into Hector's right ear.
  • Rhoda Virus (Justine Bateman) - An intestinal virus who plans on giving Hector a bad case of Gastroenteritis. Unfortunately, for her, Hector had a 12 bean salad, which gave him a gas attack, and the gas's deadly to her and her gang, so Rota disguises herself as a submarine captain to take Ozzy, Drix, and Maria into the intestines to destroy the Great White Bean. In the end, she and her henchmen are trapped in a gas bubble, killing them.
  • Protozilla (Frank Welker) - An allergen with a weak form and a monster form with his monster form only usable in a body that's allergic to him, however, Ice Pills causes him to revert back to his normal form. His most defining feature's that he has 2 thumbs which gives him away as the allergy. He was a giant monster that terrorized the city of Hector and made it look like it that it was Drix's dog who was causing the disaster (meanwhile, outside of Hector, Hector himself had a dog and his mother believed that the dog was making him sneeze). Then Ozzy, Drix and Drix's dog confronted Protozilla in Hector's nose and when Hector sneezed, Protozilla was blown out and killed. And back with Hector, it was revealed that was making him sneeze, it really from flowers his mother was bringing in and not the dog.
  • Smirch (Danny Bonaduce) - An acne germ that plans to make Hector get a zit ("Street Up"). He also managed to trick Drix when he wanted to learn how to be "Street Wise". Actually, Drix helped him to get into a sebum oil refinery, so, he had an opportunity to grow gigantic and give Hector a zit, right on School Picture Day. Then Drix defeats him by dropping sodium bicarbonate toothpaste on him, shrinking him down to a tiny size, then Chief Gluteus put him in his shirt pocket.
  • Nick O' Teen (Tim Curry) - A tobacco addictive that plans to make Hector addicted to smoking ("Where There's Smoke"). Nick can shapeshift and release clouds of smoke that can brainwash cells and make them do Nick's evil bidding, becoming more powerful the more cells he controls. He has three henchmen, Butane (Jeff Bennett), Carbon Monoxide (Tara Strong), and Tar (Frank Welker). Nick's henchmen were killed before him in confrontations with Ozzy and Drix, but when Nick was finally powerful enough to hold Ozzy and Drix back from foiling his plans, Hector decided not to smoke Cigarettes anymore in Christine's favor, and then Nick was weakened by him breaking the addiction, then Ozzy squished him under his shoe.
  • Sal Monella (Henry Winkler) - A gangster germ who enters the city of Hector on a Rusty Dog, which Hector didn't know that it was tainted, and plans to dump illegal toxic waste in Hector's stomach. To make matters worse, Mayor Spryman was in his hostage. But his plans were destroyed when Ozzy and Drix made Hector barf by going on a ride at Rustyland called "The Barfy Bungee", and the mayor was rescued and brought back to the city.
  • Sylvian Fisher (Brian Posehn) - A nerdy brain cell who was trying to become mayor in the upcoming election. He planned to use a growth formula to make Hector grow uncontrollably and blame it on Spryman's carelessness. His name comes from the Sylvian fissure brain area.
  • General Malaise (Charlie Adler) - A bacterium who uses sugar to make his army of bacteria multiply. He develops evil plots to make Hector eat sugar. Of course, he and all his troops were killed when they were in Hector's teeth and when he was visiting the dentist. They fell out through a sink to die off. They also dissolve when they eat salt. General Malaise's an obvious parody of Napoleon Bonaparte.
  • Professor Nightmare (Keith Silverstein) - A nightmare that originated from a movie Hector saw. Ozzy and Drix enter Hector's dreams and help him overcome his fear and crush him.
  • Chief Maximus (Rob Paulsen) - The Chief of Police in the city of Christine (a girl that Hector likes) that teams up with the Pneumoniac.
  • The Pneumoniac (Pat Fraley) - A germ who is planning to give Christine pneumonia ("An Out of Body Experience parts 1 & 2").
  • Mother Worm (Frank Welker) - A Trichinella spiralis Worm that came from a Sausage Hector barely cooked. It's very reminiscent of Japanese monsters especially Godzilla, even having atomic breath. If it had been left unchecked, she could've caused a massive outbreak of trichinosis. She was killed by having medicine shoved down her throat, causing her to explode. The hunt for the Worm's an obvious parody of the film "Jaws."
  • Shane (Danny Cooksey) - A hormone leader of a testosterone gang that once tied up Mayor Spryman and took control over the Brain, turning common sense off and transforming Hector into a bad kid.
  • Stickety Lipid (Rob Paulsen) - A sticky, bad cholesterol beatnik who kidnaps a bunch of fat cell kids in an attempt to clog Hector's artery. He sees what he doesn't as crimes, but as art.
  • Cryo (Susan Silo) - A virus that once tried to give Hector Hypothermia, despite the fact that Hypothermia is when the core temperatures of the body decrease to a critical level. Therefore, it is not a disease. She has the ability to fire freezing blasts from her elbows. She was eventually destroyed when struck by a nerve impulse from Hector's spine.
  • Pb (Jeff Bennett) - is the leader of the Lead Head gang. He was from a lead-painted shed that was painted in the 1960's, before 1974, when the government banned lead in paint. When Hector sniffed some paint dust, Pb and his boys infect Hector. But thanks to Ozzy, Drix, and the Supplements, the Lead Heads were dropped into the bladder, and flushed out of Hector.
  • Mitosis Jones (Phil LaMarr) - Ozzy's evil and mutated clone who understands that due to his mutation, the city of Hector will reject him. So he plans to take Ozzy's place on the iodine detail and steal it, and without the iodine, Hector cannot grow. At the end of the episode, Mitosis was rejected and lived in the body of Uno, Hector's pet dog, where he was happy.
  • Billy Bob Bile (Frank Welker) - A stereotypical Hillbilly and owner of an appendix hotel who was causing detours which it resulted in Hector's appendix almost bursting. Only a quick trip to a hospital saved Hector's life and then the Doctor there removed Billy's hotel. Billy attempted to return to civilization, only to cause Ozzy and Drix to slap cuffs on his wrists. When he tries to escape, he took a trip to the Small Intestine.

Episode list[edit | edit source]

Note: Several episodes borrow several footage from the film Osmosis Jones.

Season 1: 2002-2003[edit | edit source]

# Title Original airdate Production code
1 "Home With Hector" September 14, 2002 (2002-09-14)
By way of a simple mosquito bite, Ozzy and Drix are transferred from Frank and into the body of a 13-year old boy, Hector. Unfortunately, a nasty germ named Scarlet Fever is also transferred, and our heroes have to capture him before he wreaks havoc on the City of Hector.
2 "Reflex" September 21, 2002
Ozzy accidentally produces a neural spasm that causes Hector to kick Ricky the school bully. When Rick threatens to beat up Hector after school, Ozzy has to figure out a way to help Hector defend himself. In the end, Ozzy manages to scare Rick by controlling Hector.
3 "Strep-Finger" September 28, 2002
Ozzy becomes jealous of a super agent (Penicillin G.) who has been injected into Hector to track down a powerful germ known as Strepfinger.
4 "A Lousy Haircut" October 5, 2002
When Ozzy discovers there are lice eggs in Hector's hair, he and Drix venture onto the scalp to knock the eggs off, only to end up running into the monstrous Mother Louse!
5 "Oh My Dog" October 12, 2002
Drix's new pet dog, Dander, is mistaken for an Allergen that is threatening the city, while, outside Hector, Mrs. Cruz thinks that it is Hector's dog causing the allergy that Hector is suffering from.
6 "Street Up" October 19, 2002
Drix tries to learn how to act "street" and ends up helping an acne germ create a huge zit on Hector's face -- right on Picture Day!
7 "Gas of Doom" November 9, 2002
Ozzy, Drix, and Maria commandeer a submersible police craft into the intestines to stop a gas build-up that threatens Hector's social situation.
8 "Where There's Smoke" November 16, 2002
Ozzy and Maria must keep Nick O'Teen from getting to the brain where he will cause Hector to smoke.
9 "The Globfather" November 30, 2002
When Sal Monella, a poisonous gangster germ, kidnaps the Mayor with plans to poison Hector, Ozzy and Drix must come to his rescue.
10 "Ozzy Jr." December 7, 2002
Ozzy thinks he's going to have a baby, but it turns out he's been infected with an intracellular bacteria by returning villain Strepfinger. Maria and Drix must find a way to destroy the parasite growing within Ozzy before it spreads its infection to all of Hector. The parasite grows to monstrous proportions, exits Ozzy, and is eventually destroyed when Drix finds it is killed by pastry products.
11 "Growth" February 1, 2003
The Mayoral election is coming up, and Spryman's opponent, a nerdy brain cell named Sylvian Fisher, is using a secret growth formula to cause destructive unnatural growth spurts and make the Mayor look bad. Ozzy and Drix must stop this fiendish plan, which becomes more difficult when Sylvian takes the growth formula himself and becomes a raging, muscular monster.
12 "Sugar Shock" February 8, 2003
Hector binges on candy, creating a sugar rush that speeds up all the cells and causes the bacteria population to swell. When his parents cut him off sugar, his drop in blood sugar slows all the cells to a crawl. But the bacteria need sugar, so they form an army to raid Hector's sugar reserves. Now Drix and an extremely sleepy Ozzy, with the help of the Mole, must take on the bacterial army.
13 "The Dream Factory" March 1, 2003
After seeing a scary movie, Hector's terrible recurring nightmare is keeping everyone in the City of Hector awake. Ozzy and Drix go to the "Subconscious Network," where dreams are produced, and enter Hector's nightmare to help him face his fear. Unfortunately, whatever happens to them in the dream happens for real.

Season 2: 2003-2004[edit | edit source]

# Title Original airdate Production code
14 "An Out of Body Experience Part 1" August 23, 2003
Ozzy accidentally gets transferred into a girl named Christine's body when she gives Hector mouth-to-mouth after he jumps off the high dive to impress her. While there, Ozzy starts changing colors and acting like a girl and gets arrested because they think he is a virus.
15 "An Out of Body Experience Part 2" August 30, 2003
While Ozzy is still in Christine, using REM sleep (or Rapid Eye Movement), he calls Drix for help, and that's when he learns he's gender morphing. When a cell from a certain gender goes to a body of another gender, that cell becomes that gender. With Drix's plan, and the help of another Drixenol cold pill in Christine called "Drixeen," Ozzy comes back to Hector, and keeps Christine from having pneumonia.
16 "Lights Out!" September 6, 2003
Everyone inside Hector forgets who Ozzy and Drix are when Hector experiences a concussion, forcing them to locate the site of the concussion, so they can reboot Hector's memories before Hector crashes.
17 "The Conqueror Worm" September 13, 2003
Hector eats a barely cooked sausage and gets sick, leading him to getting two worms (probably tapeworms) in his body. The male worm dies, but the female survives. Ozzy, Drix and Maria and a crazy captain must try to kill it.
18 "Puberty Alert" September 20, 2003
Hector discovers hair growing on his chin; the testosterone gang ties up the Mayor and wreaks havoc.
19 "Tricky Ricardo" September 27, 2003
After getting injured on a police case, Maria is sent home to rest for the week. She decided to use this time to work on a family reunion coming up for her. Drix notices a rip on the corner of Maria's family picture. Maria does not seem to want to talk about it but then her brother, Ricky comes in and starts putting the puzzle pieces together. Maria and Ricky share their past with Drix which turns out as Ricky being the family prankster. Maria lost her trust in him so Drix decides to help Ricky get it back. He allows him to be a private eye along with Ozzy with good results and Ricky actually becomes one of the best. Unfortunately, Ricky is working for Strepfinger, who plots to create a tumor out of Drix's medications, but now Ricky is reluctant to hurt Maria again.
20 "Aunti Histamine" October 4, 2003
Hector uses a nose spray to clear his nose, and Drix's aunt appears. Suddenly, there's a drop in water levels in Hector and Ozzy thinks Drix's aunt is causing it.
21 "A Growing Cell" October 11, 2003
Hector is super-sizing at fast-food restaurants far too much which not only makes him a little chubby, but it also gives Sticity, a bad cholesterol beatnik, the chance to kidnap a fat cell family's child, in an attempt to clog an artery. Can Ozzy and Drix (and the new navigational system, installed by Drix, named Backseat) return the huge blob to his parents in time, and can Hector stop his gut from getting any bigger?
22 "A Cold Day in Hector" February 25, 2004
While snowboarding with Travis, Hector crosses an off limits area. Hector starts to freeride, but falls and rips his snowsuit. This causes a virus named Cryo to drop Hector's temperature. Ozzy and Drix were getting ready for a day at the beach, but now have to stop Cryo from making Hector die of hypothermia.
23 "Supplements (a.k.a. Triumph of the Supplements)" June 14, 2004
When Hector accidentally breathes in lead while helping his dad strip old paint off of a shed, the Lead Gang cause him to feel ill. The Mayor then makes Hector eat cereal so he can bring in the Supplements.
24 "Double Dose (a.k.a. Ozzy & Ozzy)" June 21, 2004
Ozzy goes into mitosis and a four armed evil clone doubles from him, trying to steal the iodine that will allow Hector to grow.
25 "Nature Calls" June 28, 2004
Billy Bob Bile creates a detour away from the small intestine so bacteria will come to his hotel. Ozzy, Drix and Maria, who are camping and forced to work at the hotel and must stop Bile before Hector's appendix bursts.
26 "Cavities (a.k.a. Journey to the Center of the Tooth)" July 5, 2004
Series Finale. Hector eats too much sugar and doesn't brush so he gets a cavity caused by General Malaise, who is going to cause further pain when Hector goes to the dentist. Meanwhile, Drix must overcome his claustrophobia.

External links[edit | edit source]

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