Ozzy & Drix is an American animated television series and a spin-off series, based on the film Osmosis Jones. The series follows the adventures of white blood cell cop, Ozzy and his partner, over-the-counter cold pill Drix, as they defend the City of Hector, inside the body of a 13-year-old boy.
The show premiered on Kids' WB on September 14, 2002, and later aired in Cartoon Network on October 4, 2004. The show ran until the final episode aired on Kids' WB on July 5, 2004 and November 22, 2004 on Cartoon Network.
Summary[]
A year after Ozzy and Drix defeated Thrax and saved Frank from dying in Osmosis Jones, Ozzy and Drix chase a scarlet fever bacterium (possibly due to Frank resuming his poor eating habits) and end up getting sucked up from Frank along with the germ by a mosquito and arrive on a teenager named Hector Cruz. After some initial problems with their new home, both are installed as Private Investigators, vowing to protect the well being of Hector from any viral threat.
Characters[]
Main characters[]
- Osmosis "Ozzy" Jones (voiced by Phil LaMarr) - An urban and funky white blood cell with little respect for authority and one of the two titular protagonists of the show. He works as a private-eye in the city of Hector. He and Drix were originally from the city of Frank, the character portrayed in the movie, although they were transferred to Hector through a mosquito while chasing a evil scarlet fever virus aptly named Scarlet. As most crime-fighting heroes do, Ozzy has a nearly unlimited amount of smart remarks that he uses frequently when fighting viruses, as well as sarcasm for anyone else.
- Agent Drixobenzometapetramine/Drixenol "Drix" Koldriliff (voiced by Jeff Bennett) - A straight-laced and by-the-book cold pill and Ozzy's fellow private eye and best friend, and the one of the two titular protagonists of the show. They have an office inside Hector's left retina ("prime real estate"). His right arm is a multi-launcher which launches various chemical containers stored in his torso though the most common is an ice pill which freezes villains. The right arm also contains a phone, and other gadgets including an eggbeater (apparently the only thing the arm can't do is make a decent milkshake),and a crude clamp-like claw usable as a hand. Drix's cautiousness and complete honesty (making him quite gullible), puts him at odds with the devil-may-care Ozzy. He often tries to "fit in" with the other cells in the body, usually failing to comprehend the concepts. He is fun-loving, happy go-lucky, and sometimes a comic relief and a coward instead of being tough and serious, unlike in the movie.
- Hector Cruz (AKA The City of Hector) (voiced by Justin Cowden) - A Cuban-American teenager that the show revolves around. He is foolhardy, a risk taker, and somewhat ignorant, all probably to further the show's plot. He reminds Ozzy of Frank at Hector's age, reminded him that this was the age where Frank's life took a turn for the worse so decides to stay to prevent that from happening. Hector has a dog named Uno, an older sister, and a mother and father. He is the deuteragonist of the show.
The City of Hector[]
Police[]
- Maria Amino (voiced by Tasia Valenza) - A white blood cell and a cop in the city of Hector. She speaks with a Hispanic accent. She is highly skilled at fighting and possibly the most competent cop inside of Hector except for Ozzy. She has shown to have a crush on Drix throughout the series. Her name comes from the term amino acid and is also Drix's love interest. She is the tritagonist of the show.
- Chief Gluteus (voiced by Jim Cummings) - A gruff, stern old muscle cell and the Chief of Police for the City of Hector. He often prefers to handle things himself, which usually results in disasters. His name comes from Gluteus Maximus, the scientific name for the muscles in the buttock.
Government[]
- Mayor Paul Spryman (voiced by Alanna Ubach) - He is the teenage mayor of the city of Hector, and Ozzy's rival. Unlike Mayor Phlemming, who was an adult that acted mature and gentlemen-like, Spryman is approximately the same age as Hector, and acts very immaturely, and often takes all the credit for the round-ups Ozzy and Drix make. His decisions often put Hector's health in extreme danger as well as sometimes being completely ridiculous, where Maria commented that he once ordered all the cells to go to the left side to see if Hector would tip over.
- Ellen Patella (voiced by Vivica A. Fox) - An attorney-at-law who helps new cells find their place in Hector. Ozzy has a small crush on her as well, although she has no interest in him.
Others[]
- The Mole (voiced by Jeffrey Tambor) - A former secret agent, and a klutz who is generally used as comic relief. He has his own adrenaline supply, and in every one of his appearances he tries to "vanish mysteriously" (failing to do so every time in comical ways). He is mostly known as very paranoid, often thinking that he is being hunted down, or people are watching him. Despite this he has a lot of contacts and apparently nothing happens in Hector that he doesn't know about, this makes him a good source of information. His role is similar to that of the flu shot from the movie.
- Penicillin G (voiced by Julian Sands) - A Penicillin injected into Hector to help fight Strepfinger. He is charming, responsible, and amazingly intelligent. He currently patrols Hector's lungs. He is an obvious parody of James Bond.
- Sticky Flagella (voiced by Wendie Malick) - TBA
- Dander (voiced by Frank Welker) - He is Drix's pet dog germ that came from Hector's dog Uno, formed from the dog's saliva inside Hector's nostril. Like cells, he can shapeshift and often changes his head into Ozzy.
- Auntie Histamine (voiced by Andrea Martin) - She is Drix's aunt, who used to read lists of synthesized amino acids to Drix when he was young, but she accidentally became a villain when Hector abuses his nose spray when he had a cold. So when Hector uses the spray, Auntie becomes hysterical and drains all the liquids on Hector, which could have been damaging to his nose.
- Backseat (voiced by Rob Paulsen) - TBA
- Agoopus Glop (voiced by Charlie Adler) - He is a young fat cell who was once kidnapped by Stickity Lipid. His parents are Daddy Glop and Mumsy Glop.
The Supplements[]
- Vitamin A (voiced by Phil LaMarr) - He is the leader of the Supplements who lead his team to victory by stopping the Lead-Heads who were attempting to infect Hector. Unlike Ozzy, he is very by-the-book, and bears a slight resemblance to Superman.
- B Complex (voiced by Jim Cummings) - B Complex has three heads (which are usually arguing with one another) and four legs, but only two arms.
- Iron (voiced by Phil LaMarr) - He is a strong, yet short-tempered, member of the Supplements, and the only one with no cape. Iron is a parody of the Thing of the Fantastic Four.
- Vitamin D (voiced by Rob Paulsen) - He is a fast, egotistical member of the Supplements.
- Vitamin E (voiced by Nancy Lenari) - She is the only female member of the Supplements, who encouraged Drix to join the team. She has three eyes.
Help from the City of Hector[]
- Captain Quinine (voiced by James Belushi) - A tonic water-based captain who lost his leg in a stomach acid accident (parodying Captain Ahab of Moby Dick).
- The Current Dreams Studio Head (voiced by Kevin Michael Richardson) - A small studio head of the subconscious network, who used a holographic head to appear more powerful and scary, like the titular character of The Wizard of Oz.
- Loretta Epstein-Barr (voiced by Kathy Najimy) - The vice president of the subconscious network, who explained why the studio kept rerunning the nightmare Hector was having.
- Ricardo "Ricky" Amino - TBA
Humans[]
- Mr. Cruz (voiced by Joe Lala) - Hector's father is helpful and kind, but he is very strict, stern, serious and strongly observant when it comes to Hector's health, attitude, and school reports.
- Mrs. Cruz (voiced by Alanna Ubach) - Hector's mother is always looking out for Hector's health, since he is still a teenager and doesn't listen to her sometimes.
- Hector's sister (voiced by Alanna Ubach) - She is always starting an argument with Hector, because she is the older sister.
- Christine Kolchuck (AKA The City of Christine) (voiced by Kimberly Brooks) - She is very sweet, not to mention Hector's crush. Ozzy even helped save Christine from the Pneumoniac. She is also Hector's love-interest.
- Travis Lurn (voiced by Rob Paulsen) - He is Hector's best friend.
- Ricky Sales (voiced by Rob Paulsen) - He is the bully at Hector's school, and the main antagonist in the episode "Reflex".
- Frank DeTorre - He was Ozzy and Drix's original host body, who had recently gone back to his poor eating habits.
- Jude (voiced by Rino Romano) - TBA
- Ashley (voiced by Tara Strong) - TBA
- Hector's French teacher - TBA
Animals[]
- Uno - He is Hector's dog, as well as the original host body of Drix's dog, Dander.
- Travis' cat - It is the apparent pet cat of Hector's friend Travis. The cat only appeared in "Gas of Doom", wherein it played a tuba as part of Travis' science fair project.
The City of Christine[]
- Mayor Conscious Santorini (voiced by Cree Summer) - She is the mayor of Christine, who is smarter and more responsible than Spryman. She even said that everyone in Christine are fans of Hector.
- Cilia Tyson (voiced by Dawnn Lewis) - Cilia is a cop in Christine who helped Ozzy stop the Pneumoniac and prove that Maximus is a traitor to the city. She was made the new police chief by the mayor. She used to dislike Ozzy.
- Drixeen (AKA Agent Drixeenaphetametamine) (voiced by Miriam Flynn) - She is a friend to Cilia and she used to be a cold pill. She looks a bit like Drix, except that she is green and yellow, has blonde hair styled into a beehive, and a cannon in place of her left hand (as opposed to Drix's cannon, which is located on his right arm). Drixine also wears green lipstick and cat-eye glasses.
Germs, Viruses, and Other Ailments[]
- Scarlet Fever (voiced by Tim Curry) - TBA
- Ernest Strepfinger (voiced by Brad Garrett (Season 1), Jim Cummings (Season 2)) - A powerful germ whose goal is to make Hector sick. He has a large gang of germs and viruses to do his dirty work. In "Strepfinger", Strepfinger is planning on giving Hector a nasty case of pneumonia, but in the end, he gets sucked out from his hideout in the lungs along with his pet. In "Ozzy Jr.", Strepfinger returns, but this time he has an eye patch on his right eye and his pet has an eye patch, too. He plans to infect Hector with bacteria. In "Lights Out", Ozzy and Drix use his resources to break into the Central Data Bank when everyone forgets who they are after Hector suffers a concussion. In "Tricky Ricardo", he tricks Ricardo into thinking that he's working for Strepfinger, who was planning to give Hector Cancer, but in the end, Strepfinger gets stuck on one of the cotton balls and fell down the drain of the shower. Strepfinger is a parody of the stereotypical Bond villain with a particular emphasis on Auric Goldfinger and Ernst Stavro Blofeld.
- Mother Louse - A louse that laid its eggs in Hector's hair. It fell to its death when Drix got too close to one of Hector's hairs, but he caught Ozzy just in time and then he and Ozzy went into Hector's right ear.
- Rhoda Virus (voiced by Justine Bateman) - An intestinal virus who plans on giving Hector a bad case of Gastroenteritis. Unfortunately for her, Hector had a 12 bean salad, which gave him a gas attack, and the gas is deadly to her and her gang, so Rhoda disguises herself as a submarine captain to take Ozzy, Drix, and Maria into the intestines to destroy the Great White Bean. In the end, she and her henchmen are trapped in a gas bubble, killing them.
- Protozilla (voiced by Frank Welker) - An allergen with a weak form and a monster form with his monster form only usable in a body that's allergic to him, however, Ice Pills causes him to revert back to his normal form. His most defining feature's that he has 2 thumbs which gives him away as the allergy. He was a giant monster that terrorized the city of Hector and made it look like it that it was Drix's dog who was causing the disaster (meanwhile, outside of Hector, Hector himself had a dog and his mother believed that the dog was making him sneeze). Then Ozzy, Drix and Drix's dog confronted Protozilla in Hector's nose and when Hector sneezed, Protozilla was blown out and killed. And back with Hector, it was revealed that was making him sneeze, it really from flowers his mother was bringing in and not the dog.
- Smirch (voiced by Danny Bonaduce) - An acne germ that plans to make Hector get a zit in "Street Up". He also managed to trick Drix when he wanted to learn how to be "Street Wise". Actually, Drix helped him to get into a sebum oil refinery, so, he had an opportunity to grow gigantic and give Hector a zit, right on School Picture Day. Then Drix defeats him by dropping sodium bicarbonate toothpaste on him, shrinking him down to a tiny size, then Chief Gluteus put him in his shirt pocket.
- Nick O' Teen (voiced by Tim Curry) - A tobacco addictive that plans to make Hector addicted to smoking ("Where There's Smoke"). Nick can shapeshift and release clouds of smoke that can brainwash cells and make them do Nick's evil bidding, becoming more powerful the more cells he controls. He has three henchmen, Butane (voiced by Jeff Bennett), Carbon Monoxide (voiced by Tara Strong), and Tar (voiced by Frank Welker). Nick's henchmen were killed before him in confrontations with Ozzy and Drix, but when Nick was finally powerful enough to hold Ozzy and Drix back from foiling his plans, Hector decided not to smoke Cigarettes anymore in Christine's favor, and then Nick was weakened by him breaking the addiction, then Ozzy squished him under his shoe.
- Sal Monella (voiced by Henry Winkler) - A gangster germ who entered the City of Hector on a Rusty Dog, which Hector didn't know was tainted, and plans to dump illegal toxic waste in Hector's stomach. To make matters worse, Mayor Spryman was in his hostage. But his plans were destroyed when Ozzy and Drix made Hector barf by going on a ride at Rustyland called "The Barfy Bungee", and the mayor was rescued and brought back to the city.
- General Malaise (voiced by Charlie Adler) - A bacterium who uses sugar to make his army of bacteria multiply. He develops evil plots to make Hector eat sugar. Of course, he and all his troops were killed when they were in Hector's teeth and when he was visiting the dentist. They fell out through a sink to die off. They also dissolve when they eat salt. He is an obvious parody of Napoleon Bonaparte.
- Professor Nightmare (voiced by Keith Silverstein) - A nightmare that originated from a movie Hector had seen called ". Ozzy and Drix enter Hector's dreams and help him overcome his fear and crush him.
- The Pneumoniac (voiced by Pat Fraley) - A germ who planned to give Christine pneumonia in "An Out of Body Experience parts 1 & 2".
- Mother Worm (voiced by Frank Welker) - A Trichinella spiralis worm that came from a sausage that Hector did not cook properly. It is highly reminiscent of Japanese monsters such as Godzilla, and even has atomic breath. If it had been left unchecked, she could've caused a massive outbreak of trichinosis. She was killed by having medicine shoved down her throat, causing her to explode. The hunt for the Worm is an obvious parody of the film Jaws.
- Shane (voiced by Danny Cooksey) - A hormone leader of a testosterone gang that once tied up Mayor Spryman and took control over the Brain, turning common sense off and transforming Hector into a bad kid.
- Stickity Lipid (voiced by Rob Paulsen) - A sticky bad cholesterol beatnik who kidnaps a bunch of fat cell kids in an attempt to clog Hector's artery. He doesn't consider himself a criminal, but an artist, though Maria says that no one else shares his sentiment.
- Cryo (voiced by Susan Silo) - A virus who once tried to give Hector Hypothermia (despite the fact that Hypothermia is when the core temperatures of the body decrease to a critical level, and is therefore not a disease). She has the ability to fire freezing blasts from her elbows. She was eventually destroyed when she was struck by a nerve impulse from Hector's spine.
- Pb (voiced by Jeff Bennett) - He is the leader of the Lead Head Gang, who were from a lead-painted shed that was painted in the 1960s, before the government banned lead in paint. When Hector sniffed some paint dust, Pb and his boys infect Hector. But thanks to Ozzy, Drix, and the Supplements, the Lead Heads were dropped into the bladder, and flushed out of Hector.
- Billy Bob Bile (voiced by Frank Welker) - A stereotypical Hillbilly and owner of an appendix hotel who was causing detours which it resulted in Hector's appendix almost bursting. Only a quick trip to a hospital saved Hector's life and then the Doctor there removed Billy's hotel. Billy attempted to return to civilization, only to cause Ozzy and Drix to slap cuffs on his wrists. When he tries to escape, he took a trip to the Small Intestine.
Good Cells gone Bad[]
- Sylvian Fisher (voiced by Brian Posehn) - A nerdy brain cell who was trying to become mayor in the upcoming election. He planned to use a growth formula to make Hector grow uncontrollably and blame it on Spryman's carelessness. His name comes from the area of the brain known as the Sylvian fissure.
- Chief Maximus (voiced by Rob Paulsen) - The Chief of Police in the City of Christine who teams up with the Pneumoniac.
- Mitosis Jones (voiced by Phil LaMarr) - Ozzy's evil and mutated clone who understands that due to his mutation, the city of Hector will reject him. So he plans to take Ozzy's place on the iodine detail and steal it, and without the iodine, Hector cannot grow. At the end of the episode, Mitosis was rejected and lived in the body of Uno, Hector's pet dog, where he was happy.
Trivia[]
- It was initially known as The Fantastic Voyage Adventures of Osmosis Jones & Drixenol and Osmosis Jones The Animated Series)
- There are a couple of differences of how the show was utilized from the film:
- Unlike the film, the show does not contain any live-action sequences besides the human characters from the live-action segments.
- It is slightly less violent than the movie as there are no characters who are deceased or killed off.
- Most cells and viruses in the city are portrayed as citizens like in the film.
- Most of the episodes of the series were available to watch on the Kids' WB website. However, most of the content from the website is preserved and possibly viewable under Archive.org.
- Chris Rock and David Hyde Pierce do not reprise their roles as the titular characters.
Videos[]
Promos[]
Kids' WB (2002) - Ozzy & Drix World Premiere Promo
Kids' WB 2003 Ozzy & Drix Promo
Ozzy & Drix Kids WB! TV Ad
CN city Ozzy & Drix Promo
Gallery[]
